MACORATE CR 400 MG 10 TABLETS | Valproate for Seizure Control
MACORATE CR 400 MG 10 TABLETS contain Magnesium Valproate 400 mg, a prescription anticonvulsant and mood stabilizer used for epilepsy, bipolar disorder management, and migraine prevention.
MACORATE CR 400 MG 10 TABLETS
MACORATE CR 400 MG TABLETS (Magnesium Valproate 400 mg): Comprehensive Guide and Benefits
Introduction to MACORATE CR 400 MG TABLETS
Extended-Release Antiepileptic and Mood Stabilizing Medicine
MACORATE CR 400 MG TABLETS contain Magnesium Valproate 400 mg, a prescription antiepileptic (anticonvulsant) medicine belonging to the valproate class. It is used in the management of epilepsy (seizures), bipolar disorder-associated manic episodes, and may also be prescribed for migraine prevention under medical supervision.
The controlled-release (CR) formulation helps provide gradual release of the medicine, supporting consistent therapeutic levels when taken as prescribed.
Prescription Status: Prescription-only medicine.
Key Benefits of MACORATE CR 400 MG TABLETS
Helps control abnormal electrical activity in the brain associated with seizures.
Supports prevention and management of different types of epilepsy.
Helps stabilize mood during manic episodes associated with bipolar disorder.
May help reduce the frequency of migraine attacks when prescribed for prevention.
Provides extended-release dosing for sustained medicine action.
Composition
Active Ingredient:
Magnesium Valproate – 400 mg
Dosage Form:
Controlled-Release Oral Tablet
Drug Class:
Antiepileptic / Anticonvulsant
Mood Stabilizer
Valproate Derivative
Manufacturer/Marketer:
Sun Pharmaceutical Industries Ltd.
How MACORATE CR 400 MG Works
MACORATE CR 400 MG works by reducing excessive electrical activity in the brain. Valproate increases the availability of gamma-aminobutyric acid (GABA), an inhibitory neurotransmitter that helps calm overactive nerve signalling.
This action helps:
Reduce seizure activity.
Stabilize abnormal mood changes.
Prevent migraine-related neurological overactivity.
Usage Instructions
Take MACORATE CR 400 MG TABLETS exactly as prescribed by your doctor.
Take it with food to reduce stomach-related discomfort.
Swallow the tablet whole with water.
Do not crush, chew, or break the controlled-release tablet.
Take doses at the same time each day for consistent effect.
Do not stop suddenly without medical advice, as seizure risk may increase.
Medicinal Advantages
For Epilepsy
Helps control seizures by stabilizing abnormal brain activity.
May be used alone or along with other antiepileptic medicines.
For Bipolar Disorder
Helps manage manic episodes.
Supports mood stabilization and reduces excessive mood fluctuations.
For Migraine Prevention
May decrease the frequency and severity of migraine attacks in selected patients.
Mechanism of Action
Magnesium Valproate increases inhibitory GABA activity in the central nervous system and influences ion channels involved in nerve signalling. This reduces excessive neuronal firing, helping control seizures and stabilize brain activity.
Off-Label Uses
Valproate medicines may sometimes be prescribed by specialists for certain neurological or psychiatric conditions outside approved indications based on individual patient assessment.
Use for any off-label condition should only be under medical supervision.
Expert Advice
Take MACORATE CR regularly and avoid missing doses.
Do not discontinue treatment abruptly.
Regular monitoring of liver function and blood counts may be recommended during long-term therapy.
Inform your doctor if you experience unusual tiredness, abdominal pain, severe nausea, or skin reactions.
Avoid alcohol as it may worsen dizziness and drowsiness.
Precautions
Liver Disease
Inform your doctor if you have liver problems, as valproate medicines may require careful monitoring.
Pregnancy
Valproate medicines may cause serious birth defects and developmental risks. Women who are pregnant, planning pregnancy, or of childbearing potential should discuss risks and alternatives with their doctor.
Pancreatitis
Seek medical advice if you develop severe abdominal pain, persistent nausea, or vomiting.
Kidney Problems
Inform your healthcare provider about kidney-related conditions before starting treatment.
Drug Interactions
Inform your doctor if you are taking:
Other antiepileptic medicines.
Blood thinners.
Aspirin or salicylates.
Sedatives.
Antidepressants.
Medicines affecting liver enzymes.
Possible Side Effects
Common side effects may include:
Nausea.
Vomiting.
Stomach discomfort.
Headache.
Drowsiness.
Dizziness.
Tremors.
Weight gain.
Hair thinning or hair loss.
Skin rash.
Seek immediate medical attention for severe allergic reactions, unusual bleeding, severe abdominal pain, or signs of liver problems.
Storage Instructions
Store below 30°C.
Keep in the original packaging.
Protect from moisture and direct sunlight.
Keep out of reach of children.
Frequently Asked Questions (FAQs)
Q: What is MACORATE CR 400 MG used for?
A: MACORATE CR 400 MG is used for managing epilepsy, bipolar disorder-associated manic episodes, and migraine prevention as prescribed by a doctor.
Q: What is the active ingredient in MACORATE CR 400 MG?
A: Each tablet contains Magnesium Valproate 400 mg.
Q: Is MACORATE CR 400 MG a sleeping medicine?
A: No. It is an antiepileptic and mood stabilizing medicine. Drowsiness may occur as a side effect in some patients.
Q: Can MACORATE CR 400 MG be stopped suddenly?
A: No. Sudden discontinuation may increase the risk of seizures. Always consult your doctor before changing or stopping treatment.
Q: Who manufactures MACORATE CR 400 MG TABLETS?
A: MACORATE CR 400 MG TABLETS are marketed by Sun Pharmaceutical Industries Ltd.
Product Tags
MACORATE CR 400 MG 10 TABLETS, Magnesium Valproate 400 mg, Valproate Tablet, Antiepileptic Medicine, Seizure Control Tablet, Bipolar Disorder Medicine, Migraine Prevention Medicine, Mood Stabilizer Tablet, Neurology Prescription Medicine, Sun Pharma.
